Enzymes Recombinant Proteins

Human ART4 Recombinant Protein (RPPB1415)

(No reviews yet) Write a Review
SKU:
RPPB1415
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q93070
Research Area:
Enzymes

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human ART4 Recombinant Protein
Product Code:RPPB1415
Size:5µg
Species:Human
Target:ART4
Synonyms:ARTC4, DOK1, CD297 Antigen, Dombrock Blood Group, ADP-Ribosyltransferase 4, Ecto-ADP-Ribosyltransferase 4.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:ART4 protein solution (0.25mg/ml) contains Buffered Saline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity:Greater than 85% as determined by SDS-PAGE.
Amino Acid Sequence:ADPSEVAIKI DFDFAPGSFD DQYQGCSKQV MEKLTQGDYF TKDIEAQKNY FRMWQKAHLA WLNQGKVLPQ NMTTTHAVAI LFYTLNSNVH SDFTRAMASV ARTPQQYERS FHFKYLHYYL TSAIQLLRKD SIMENGTLCY EVHYRTKDVH FNAYTGATIR FGQFLSTSLL KEEAQEFGNQ TLFTIFTCLG APVQYFSLKK EVLIPPYELF KVINMSYHPR GDWLQLRSTG NLSTYNCQLL KAHHHHHH

Ecto-ADP-Ribosyltransferase 4 or ART4 is typed as a glycosylphosphatidylinositol (GPI)-linked membrane protein which carries Dombrock blood group antigens. The development of this protein takes place at the highest levels in the fetal liver. �the process of the ART4 development is regulated while the erythroid differentiation process occurs. ART4 is a is part of the Ribosyltransferase family.

ART4 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 248 amino acids (47-285 a.a.) and having a molecular mass of 28.8kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). ART4 is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

NCBI Summary:This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008]
UniProt Code:Q93070
NCBI GenInfo Identifier:22261809
NCBI Gene ID:420
NCBI Accession:Q93070.2
UniProt Related Accession:Q93070
Molecular Weight:36kDa
NCBI Full Name:Ecto-ADP-ribosyltransferase 4
NCBI Synonym Full Names:ADP-ribosyltransferase 4 (Dombrock blood group)
NCBI Official Symbol:ART4��
NCBI Official Synonym Symbols:DO; DOK1; ARTC4; CD297; DO/ART4��
NCBI Protein Information:ecto-ADP-ribosyltransferase 4
UniProt Protein Name:Ecto-ADP-ribosyltransferase 4
UniProt Synonym Protein Names:ADP-ribosyltransferase C2 and C3 toxin-like 4; ARTC4; Dombrock blood group carrier molecule; Mono(ADP-ribosyl)transferase 4; NAD(P)(+)--arginine ADP-ribosyltransferase 4; CD_antigen: CD297
Protein Family:Ecto-ADP-ribosyltransferase
UniProt Gene Name:ART4��
View AllClose

0 Reviews

View AllClose

Related Products

Rat ART4 Recombinant Protein (RPES3753)

Rat ART4 Recombinant Protein (RPES3753)

system_update_altDatasheetRat ART4 Recombinant Protein ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier molecule an
Mouse ART4/CD297 Recombinant Protein (RPES2782)

Mouse ART4/CD297 Recombinant Protein (RPES2782)

system_update_altDatasheetMouse ART4/CD297 Recombinant Protein ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier mol
Mouse ART4/CD297 Recombinant Protein (RPES2801)

Mouse ART4/CD297 Recombinant Protein (RPES2801)

system_update_altDatasheetMouse ART4/CD297 Recombinant Protein ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier mol