Human ARRB1 / Beta Arrestin 1 ELISA Kit

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SKU:
HUFI02231
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P49407
Sensitivity:
18.75pg/ml
Range:
31.25-2000pg/ml
ELISA Type:
Sandwich
Synonyms:
ARRBeta1, ARR1, ARRB1, ARB1, ARR1, arrestin 2, Arrestin beta-1, arrestin, beta 1, beta-arrestin-1
Reactivity:
Human
Research Area:
Cell Biology

Description

Human ARRB1 / Beta Arrestin 1 ELISA

Arrestin beta 1 (ARRB1) is a cytosolic protein that serves as a cofactor in the beta-adrenergic receptor kinase (BARK) pathway, which causes desensitization of beta-adrenergic receptors. It is expressed at high levels in peripheral blood leukocytes, as a result, the BARK/beta-arrestin system is thought to have a significant role in modulating receptor-mediated immunological activities. Eiken syndrome and whim syndrome 1 are examples of ARRB1-related diseases. The RET signalling and myometrial relaxation and contraction pathways are two of the ARRB1-related pathways. The following are examples of relevant GO annotations for ARRB1: transcription factor binding and ubiquitin-protein ligase binding. ARRB2 is a paralog of ARRB1.

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