Human ARNT / HIF-1 beta ELISA Kit

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SKU:
HUFI01862
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P27540
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
ARNT, Hypoxia-inducible factor 1-beta, HIF-1-beta, HIF1-beta, Class E basic helix-loop-helix protein 2, bHLHe2, Dioxin receptor, nuclear translocator, HIF-1 beta, TANGO, ARNT protein, aryl hydrocarbon receptor nuclear translocator, BHLHE2, HIF-1 Beta
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human ARNT / HIF-1 beta ELISA

ARNT / HIF-1 beta encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. ARNT / HIF-1 beta binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. Chromosomal translocation of ARNT / HIF-1 beta with the ETV6 gene on chromosome 12 have been described in esophageal carcinoma and leukemias.

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