Human ARL5B Recombinant Protein (RPPB2793)
- SKU:
- RPPB2793
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96KC2
Description
| Product Name: | Human ARL5B Recombinant Protein |
| Product Code: | RPPB2793 |
| Size: | 20µg |
| Species: | Human |
| Target: | ARL5B |
| Synonyms: | ADP-ribosylation factor-like protein 5B, ADP-ribosylation factor-like protein 8, ARL5B, ARL8. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | ARL5B protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 30% glycerol, 0.1M NaCl and 1mM EDTA. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGLIFAKLWS LFCNQEHKVI IVGLDNAGKT TILYQFLMNE VVHTSPTIGS NVEEIVVKNT HFLMWDIGGQ ESLRSSWNTY YSNTEFIILV VDSIDRERLA ITKEELYRML AHEDLRKAAV LIFANKQDMK GCMTAAEISK YLTLSSIKDH PWHIQSCCAL TGEGLCQGLE WMTSRIGVR |
ADP-ribosylation factor-like protein 5B (ARL5B) is a member of a family of proteins which are structurally similar to ADP-ribosylation factors. ARLs and ARFs belong to the RAS superfamily of regulatory GTPases. ARL5B is most closely related to ARL5, with which it shares 80% sequence identity. Furthermore, Human ARL5B shares 100% identity with mouse ARL8 and 71% identity with the Drosophila homolog.
ARL5B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids (1-179 a.a.) and having a molecular mass of 22.5kDa.ARL5B is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ARL5B: Binds and exchanges GTP and GDP. Belongs to the small GTPase superfamily. Arf family.Protein type: G protein, monomeric; G protein, monomeric, ARFChromosomal Location of Human Ortholog: 10p12.31 |
| UniProt Protein Details: | |
| NCBI Summary: | ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.[supplied by OMIM, Nov 2010] |
| UniProt Code: | Q96KC2 |
| NCBI GenInfo Identifier: | 34922029 |
| NCBI Gene ID: | 221079 |
| NCBI Accession: | Q96KC2.1 |
| UniProt Secondary Accession: | Q96KC2 |
| UniProt Related Accession: | Q96KC2 |
| Molecular Weight: | 20,375 Da |
| NCBI Full Name: | ADP-ribosylation factor-like protein 5B |
| NCBI Synonym Full Names: | ADP ribosylation factor like GTPase 5B |
| NCBI Official Symbol: | ARL5B�� |
| NCBI Official Synonym Symbols: | ARL8�� |
| NCBI Protein Information: | ADP-ribosylation factor-like protein 5B |
| UniProt Protein Name: | ADP-ribosylation factor-like protein 5B |
| UniProt Synonym Protein Names: | ADP-ribosylation factor-like protein 8 |
| Protein Family: | ADP-ribosylation factor-like protein |
| UniProt Gene Name: | ARL5B�� |
| UniProt Entry Name: | ARL5B_HUMAN |
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