Human ARL14 Recombinant Protein (RPPB2785)
- SKU:
- RPPB2785
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8N4G2
Description
| Product Name: | Human ARL14 Recombinant Protein |
| Product Code: | RPPB2785 |
| Size: | 20µg |
| Species: | Human |
| Target: | ARL14 |
| Synonyms: | ADP-ribosylation factor-like protein 14, ADP-ribosylation factor 7, ARL14, ARF7, FLJ22595. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | ARL14 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 40% glycerol, 200mM NaCl and 1mM EDTA. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSLGSKNPQ TKQAQVLLLG LDSAGKSTLL YKLKLAKDIT TIPTIGFNVE MIELERNLSL TVWDVGGQEK MRTVWGCYCE NTDGLVYVVD STDKQRLEES QRQFEHILKN EHIKNVPVVL LANKQDMPGA LTAEDITRMF KVKKLCSDRN WYVQPCCALT GEGLAQGFRK LTGFVKSHMK SRGDTLAFFK QN |
ADP-ribosylation factor-like 14 (ARL14) is a developmentally regulated member of the ADP-ribosylation factor/ARF-like protein (ARF/ARL) family of Ras-related GTPases. ARL14 is GTPase which recruits MYO1E to MHC class II-containing vesicles via the effector protein C11orf46/ARF7EP and thus controls the movement of these vesicles along the actin cytoskeleton in dendritic cells. MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an effector protein ARF7EP.
ARL14 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 212 amino acids (1-192 a.a.) and having a molecular mass of 23.8kDa (Molecular weight on SDS-PAGE will appear higher).ARL14 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N4G2 |
| NCBI GenInfo Identifier: | 21707815 |
| NCBI Gene ID: | 80117 |
| NCBI Accession: | BC034354 |
| UniProt Secondary Accession: | Q8N4G2,Q9H655 |
| UniProt Related Accession: | Q8N4G2 |
| Molecular Weight: | 21,588 Da |
| NCBI Full Name: | Homo sapiens ADP-ribosylation factor-like 14, mRNA |
| NCBI Synonym Full Names: | ADP-ribosylation factor-like 14 |
| NCBI Official Symbol: | ARL14�� |
| NCBI Official Synonym Symbols: | ARF7�� |
| NCBI Protein Information: | ADP-ribosylation factor-like protein 14; ADP-ribosylation factor 7 |
| UniProt Protein Name: | |
| UniProt Synonym Protein Names: | |
| Protein Family: | Auxin response factor |
| UniProt Gene Name: | |
| UniProt Entry Name: |
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