Human Arachidonate 15-lipoxygenase B / ALOX15B ELISA Kit

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SKU:
HUFI01244
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O15296
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
ALOX15B, Arachidonate 15-lipoxygenase B, 15-LOX-B, 15-LOX-2, Linoleate 13-lipoxygenase 15-Lob, 15-lipoxygenase 2, Arachidonate 15-lipoxygenase type II
Reactivity:
Human
Research Area:
Metabolism

Description

Human Arachidonate 15-lipoxygenase B / ALOX15B ELISA Kit

AX15BLO encodes a lipoxygenase family of structurally similar nonheme iron dioxygenases that are involved in the formation of fatty acid hydroperoxides. Arachidonic acid is only converted to 15S-hydroperoxyeicosatetraenoic acid by the encoded protein, which metabolizes linoleic acid less effectively. AX15BLO is located in a cluster of associated genes and a pseudogene that covers about 100 kilobases on the short arm of chromosome 17. spliced transcript variants encode different isoforms which has been reported. Autosomal Recessive Congenital Ichthyosis and Embryoma Diseases caused by ALOX15B. Arachidonic acid metabolism and Folate Metabolism are the connected pathways to AX15BLO.

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