Human APP (Amyloid-beta precursor protein) ELISA Kit (HUFI03423)

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SKU:
HUFI03423
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P05067
Sensitivity:
0.563ng/ml
Range:
0.938-60ng/ml
ELISA Type:
Sandwich
Synonyms:
APP, Amyloid-beta precursor protein, ABPP, APPI, Alzheimer disease amyloid protein, Amyloid precursor protein, Amyloid-beta A4 protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, S
Reactivity:
Human

Description

Human APP (Amyloid-beta precursor protein) ELISA Kit

APP (Amyloid-beta precursor protein) is a transmembrane precursor protein that is cleaved by secretases to form peptides which can aggregate to form neurotoxic plaques in the brain. APP (Amyloid-beta precursor protein) can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation. Mutations in APP (Amyloid-beta precursor protein) have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis.

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