Cytokines Recombinant Proteins
Human APOM Recombinant Protein (RPPB0062)
- SKU:
- RPPB0062
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O95445
- Research Area:
- Cytokines
Description
| Product Name: | Human APOM Recombinant Protein |
| Product Code: | RPPB0062 |
| Size: | 10µg |
| Species: | Human |
| Target: | APOM |
| Synonyms: | G3a, HSPC336, NG20, Apolipoprotein M, APOM, Apo-M, MGC22400. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | APOM Human solution containing 20mM Tris-HCl pH-8 1mM DTT & 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MCPEHSQLTT LGVDGKEFPE VHLGQWYFIA GAAPTKEELA TFDPVDNIVF NMAAGSAPMQ LHLRATIRMK DGLCVPRKWI YHLTEGSTDL RTEGRPDMKT ELFSSSCPGG IMLNETGQGY QRFLLYNRSP HPPEKCVEEF KSLTSCLDSK AFLLTPRNQE ACELSNN |
APOM is belongs to the lipocalin protein family and is associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. APOM is secreted through the plasma membrane but remains membrane-bound, where it takes part in lipid transport. .
APOM Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 187 amino acids (23-188 a.a.) and having a molecular mass of 20.9 kDa. APOM protein is fused to a 21 amino acid His-Tag at N-terminus and purified by standard chromatography.
| UniProt Protein Function: | APOM: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. Plasma protein. Expressed in liver and kidney. Belongs to the calycin superfamily. Lipocalin family. Highly divergent. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 6p21.33 Cellular Component: integral to plasma membrane Molecular Function:antioxidant activity; lipid transporter activity; phospholipid binding Biological Process: cholesterol homeostasis; reverse cholesterol transport; response to glucose stimulus; cholesterol efflux; lipoprotein metabolic process |
| NCBI Summary: | The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012] |
| UniProt Code: | O95445 |
| NCBI GenInfo Identifier: | 17370872 |
| NCBI Gene ID: | 55937 |
| NCBI Accession: | O95445.2 |
| UniProt Secondary Accession: | O95445,Q5SRP4, Q9P046, Q9UMP6, B0UX98, |
| UniProt Related Accession: | O95445 |
| Molecular Weight: | 188 |
| NCBI Full Name: | Apolipoprotein M |
| NCBI Synonym Full Names: | apolipoprotein M |
| NCBI Official Symbol: | APOM�� |
| NCBI Official Synonym Symbols: | G3a; NG20; apo-M; HSPC336�� |
| NCBI Protein Information: | apolipoprotein M; protein G3a; NG20-like protein; alternative name: G3a, NG20 |
| UniProt Protein Name: | Apolipoprotein M |
| UniProt Synonym Protein Names: | Protein G3a |
| Protein Family: | Apomucin |
| UniProt Gene Name: | APOM�� |
| UniProt Entry Name: | APOM_HUMAN |
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