Human Apolipoprotein L1 / APOL1 ELISA Kit

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SKU:
HUFI00922
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O14791
Sensitivity:
0.469ng/ml
Range:
0.781-50ng/ml
ELISA Type:
Sandwich
Synonyms:
APOL1, Apolipoprotein L1, APOL, Apo-L, ApoL-I, Apolipoprotein L, Apolipoprotein L-I
Reactivity:
Human
Research Area:
Metabolism

Description

Human Apolipoprotein L1 / APOL1 ELISA Kit

Apolipoprotein L1/APOL1 is a secreted high-density lipoprotein that binds to apolipoprotein A-I. Apolipoprotein A-I is a plasma protein that is relatively abundant and contains the major apoprotein of HDL. Apolipoprotein L1/APOL1 is essential in the formation of most cholesteryl esters in plasma and helps to promote cholesterol removal from cells. The apolipoprotein L family member may be involved in lipid transfer and transport throughout the body, as well as reverse cholesterol transport from peripheral cells to the liver. APOL1 has been linked to a variety of diseases, including Focal Segmental Glomerulosclerosis 4 and Glomerulonephritis. Binding and uptake of ligands by scavenger receptors is one of its related pathways.

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