Human ApoER2 / LRP8 ELISA Kit

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SKU:
HUFI00857
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q14114
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
LRP8, Low-density lipoprotein receptor-related protein 8, APOER2, LRP-8, Apolipoprotein E receptor 2, Lr8b, MCI1, Apolipoprotein E R2
Reactivity:
Human
Research Area:
Cell Biology

Description

Human ApoER2 / LRP8 ELISA Kit

LRP8 is a low-density lipoprotein receptor (LDLR). Low-density lipoprotein receptors are cell surface proteins that function in signal transduction and ligand endocytosis via lysosomal degradation through the use of specific ligands. LRP8 is involved in the migration of neurons during development by regulating Reelin signaling and serves as a receptor for apolipoprotein E, the cholesterol transport protein. ApoER2/LRP8 protein may be a sign of major depressive disorder when expressed. LRP8 has been linked to myocardial infarction and osteoporosis-pseudoglioma syndrome. LRP8 is involved in the metabolism of water-soluble vitamins and cofactors, as well as GPCR signaling.

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