Human ANKRA2 Recombinant Protein (RPPB2741)

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SKU:
RPPB2741
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9H9E1

Description

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Product Name:Human ANKRA2 Recombinant Protein
Product Code:RPPB2741
Size:10µg
Species:Human
Target:ANKRA2
Synonyms:Ankyrin Repeat, Family A (RFXANK-Like), 2, ANKRA,RFXANK-Like Protein 2, Ankyrin Repeat Family A Protein 2, ANKRA2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:ANKRA2 protein solution (0.25 mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greaterthan 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMDTSTNL DIGAQLIVEE CPSTYSLTGM PDIKIEHPLD PNSEEGSAQGVAMGMKFILP NRFDMNVCSR FVKSLNEEDS KNIQDQVNSD LEVASVLFKA ECNIHTSPSP GIQVRHVYTPSTTKHFSPIK QSTTLTNKHR GNEVSTTPLL ANSLSVHQLAAQGEMLYLAT RIEQENVINH TDEEGFTPLM WAAAHGQIAV VEFLLQNGADPQLLGKGRES ALSLACSKGY TDIVKMLLDC GVDVNEYDWN GGTPLLYAVH GNHVKCVKML LESGADPTIETDSGYNSMDL AVALGYRSVQ QVIESHLLKL LQNIKE

Ankyrin Repeat Family A2, also known as ANKRA2 contains 5 ANK repeats.ANKRA2 assist endocytosis by linking megalin to components of the cytoskeletonor endocytic machinery.

ANKRA2 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 336 amino acids (1-313a.a) andhaving a molecular mass of 36.7kDa.ANKRA2 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

UniProt Protein Function:May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5 (PubMed:25752541). May also regulate LRP2/megalin ().
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9H9E1
NCBI GenInfo Identifier:15991861
NCBI Gene ID:57763
NCBI Accession:BC012917
UniProt Secondary Accession:Q9H9E1
UniProt Related Accession:Q9H9E1
Molecular Weight:34,272 Da
NCBI Full Name:Homo sapiens ankyrin repeat, family A (RFXANK-like), 2, mRNA
NCBI Synonym Full Names:ankyrin repeat family A member 2
NCBI Official Symbol:ANKRA2��
NCBI Official Synonym Symbols:ANKRA��
NCBI Protein Information:ankyrin repeat family A protein 2
UniProt Protein Name:Ankyrin repeat family A protein 2
UniProt Synonym Protein Names:RFXANK-like protein 2
Protein Family:Ankyrin repeat family A protein
UniProt Gene Name:ANKRA2��
UniProt Entry Name:
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