Human ANKRA2 Recombinant Protein (RPPB2741)
- SKU:
- RPPB2741
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9H9E1
Description
| Product Name: | Human ANKRA2 Recombinant Protein |
| Product Code: | RPPB2741 |
| Size: | 10µg |
| Species: | Human |
| Target: | ANKRA2 |
| Synonyms: | Ankyrin Repeat, Family A (RFXANK-Like), 2, ANKRA,RFXANK-Like Protein 2, Ankyrin Repeat Family A Protein 2, ANKRA2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | ANKRA2 protein solution (0.25 mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greaterthan 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMDTSTNL DIGAQLIVEE CPSTYSLTGM PDIKIEHPLD PNSEEGSAQGVAMGMKFILP NRFDMNVCSR FVKSLNEEDS KNIQDQVNSD LEVASVLFKA ECNIHTSPSP GIQVRHVYTPSTTKHFSPIK QSTTLTNKHR GNEVSTTPLL ANSLSVHQLAAQGEMLYLAT RIEQENVINH TDEEGFTPLM WAAAHGQIAV VEFLLQNGADPQLLGKGRES ALSLACSKGY TDIVKMLLDC GVDVNEYDWN GGTPLLYAVH GNHVKCVKML LESGADPTIETDSGYNSMDL AVALGYRSVQ QVIESHLLKL LQNIKE |
Ankyrin Repeat Family A2, also known as ANKRA2 contains 5 ANK repeats.ANKRA2 assist endocytosis by linking megalin to components of the cytoskeletonor endocytic machinery.
ANKRA2 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 336 amino acids (1-313a.a) andhaving a molecular mass of 36.7kDa.ANKRA2 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5 (PubMed:25752541). May also regulate LRP2/megalin (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H9E1 |
| NCBI GenInfo Identifier: | 15991861 |
| NCBI Gene ID: | 57763 |
| NCBI Accession: | BC012917 |
| UniProt Secondary Accession: | Q9H9E1 |
| UniProt Related Accession: | Q9H9E1 |
| Molecular Weight: | 34,272 Da |
| NCBI Full Name: | Homo sapiens ankyrin repeat, family A (RFXANK-like), 2, mRNA |
| NCBI Synonym Full Names: | ankyrin repeat family A member 2 |
| NCBI Official Symbol: | ANKRA2�� |
| NCBI Official Synonym Symbols: | ANKRA�� |
| NCBI Protein Information: | ankyrin repeat family A protein 2 |
| UniProt Protein Name: | Ankyrin repeat family A protein 2 |
| UniProt Synonym Protein Names: | RFXANK-like protein 2 |
| Protein Family: | Ankyrin repeat family A protein |
| UniProt Gene Name: | ANKRA2�� |
| UniProt Entry Name: |
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