Human AMIGO2 Recombinant Protein (RPPB2731)

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SKU:
RPPB2731
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q86SJ2

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human AMIGO2 Recombinant Protein
Product Code:RPPB2731
Size:10µg
Species:Human
Target:AMIGO2
Synonyms:AdhesionMolecule with Ig-Like Domain 2, Differentially Expressed in Gastric, Adenocarcinomas,AMIGO-2, ALI1, DEGA, Differentially Expressed in Gastric, Adenocarcinoma, Amphoterin-InducedGene and Open Reading Frame 2, Transmembrane Protein AMIGO2, Amphoterin InducedGene, Alivin 1, Alivin-1.
Source:Sf9 Insect cells
Physical Appearance:Sterilefiltered colorless solution.
Formulation:AMIGO2protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greaterthan 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:VCPTACICAT DIVSCTNKNL SKVPGNLFRL IKRLDLSYNR IGLLDSEWIP VSFAKLNTLILRHNNITSIS TGSFSTTPNL KCLDLSSNKL KTVKNAVFQE LKVLEVLLLY NNHISYLDPS AFGGLSQLQK LYLSGNFLTQ FPMDLYVGRF KLAELMFLDV SYNRIPSMPM HHINLVPGKQ LRGIYLHGNP FVCDCSLYSL LVFWYRRHFS SVMDFKNDYT CRLWSDSRHS RQVLLLQDSF�MNCSDSIING SFRALGFIHE AQVGERLMVH CDSKTGNANT DFIWVGPDNR LLEPDKEMEN FYVFHNGSLV IESPRFEDAG VYSCIAMNKQ RLLNETVDVT INVSNFTVSR SHAHEAFNTL�EHHHHHH

Adhesion Molecule with Ig-Like Domain 2, also known as AMIGO2 is a memberof the leucine-rich repeat family. AMIGO2 arbitrates homophilic in addition toheterophilic cell-cell interaction with AMIGO1 or AMIGO3. Furthermore, AMIGO2 contributes to signal transduction via its intracellular domain and isalso essential for tumorigenesis of a subset of gastric adenocarcinomas.

AMIGO2 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 367 amino acids (40-398a.a.) and having a molecular mass of 41.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).AMIGO2 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q86SJ2
NCBI GenInfo Identifier:219521831
NCBI Gene ID:347902
NCBI Accession:NP_001137140.1
UniProt Secondary Accession:Q86SJ2,Q4VBP6, Q7Z4A0, Q96CN8
UniProt Related Accession:Q86SJ2
Molecular Weight:57
NCBI Full Name:amphoterin-induced protein 2
NCBI Synonym Full Names:adhesion molecule with Ig like domain 2
NCBI Official Symbol:AMIGO2��
NCBI Official Synonym Symbols:ALI1; DEGA; AMIGO-2��
NCBI Protein Information:amphoterin-induced protein 2
UniProt Protein Name:Amphoterin-induced protein 2
UniProt Synonym Protein Names:AMIGO-2; Alivin-1; Differentially expressed in gastric adenocarcinomas; DEGA
Protein Family:
UniProt Gene Name:AMIGO2��
UniProt Entry Name:
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