Human AMIGO2 Recombinant Protein (RPES4645)
- SKU:
- RPES4645
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human AMIGO2 Recombinant Protein
Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain; 6 LRR (leucine-rich) repeats; a LRRCT domain; as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast; ovary; cervix; and uterus; although lower in lung; colon; and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain; and may be required for tumorigenesis of a subset of gastric adenocarcinomas.
| Product Name: | Human AMIGO2 Recombinant Protein (RPES4645) |
| Product Code: | RPES4645 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Amphoterin-Induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in Gastric Adenocarcinomas, DEGA, ALI1 |
| Accession: | Q86SJ2 |
| Sequence: | Val40-His393 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human AMIGO2 is produced by our Mammalian expression system and the target gene encoding Val40-His393 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 41.34 kDa |
| AP Mol Mass: | 68 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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