Human Alpha-Synuclein/SNCA Recombinant Protein (RPES4685)

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SKU:
RPES4685
Product Type:
Recombinant Protein
Species:
Human

Description

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Human Alpha-Synuclein/SNCA Recombinant Protein

Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed in the brain and other tissues, albeit at lower levels. UCHL1; Phospholipase D and histones interact with SNCA. Beta- and gamma-synuclein are two forms of SNCA. SNCA is also a key regulator of vesicular transport in neurons. It has been postulated that SNCA is involved in the development of Parkinson's Disease and other neurodegenerative diseases. Dementia Lewy Body (DLB) can be caused by SNCA abnormalities. Human Alpha-Synuclein/SNCA Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

Product Name:Human Alpha-Synuclein/SNCA Recombinant Protein (RPES4685)
Product Code:RPES4685
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Alpha-Synuclein, Non-A Beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1
Accession:P37840
Sequence:Met1-Ala140
Activity:Recombinant Human alpha -Synuclein is ideal for use as a control substrate for in vitro Ubiquitin conjugation using select Ubiquitin E3 ligases such as CHIP/Stub1. Aggregation T1/2 time of 70 µM human alpha -Synuclein protein is 1.07h(0.5 mM SDS).
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human SLAMF6 is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:14.46 kDa
AP Mol Mass:17 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS;PH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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