Human AKR1C4 Recombinant Protein (RPES2308)

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SKU:
RPES2308
Product Type:
Recombinant Protein
Species:
Human

Description

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Human AKR1C4 Recombinant Protein

Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-?-Androstan-3-?,17-β-diol (3-?-diol). In addition, AKR1C4 also has some 20-?-Hydroxysteroid Dehydrogenase activity.

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