Human AIF / Apoptosis Inducing Factor ELISA Kit

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SKU:
HUFI02190
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O95831
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
AIF, AIFM1, COXPD6, PDCD8, AIFapoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated, 1, COXPD6, MGC111425, PDCD8striatal apoptosis-inducing factor, programmed cell death 8, apoptosis-inducing factor, Programm
Reactivity:
Human
Research Area:
Cell Death

Description

Human AIF / Apoptosis Inducing Factor ELISA Kit

AIF / Apoptosis Inducing Factor encodes a flavoprotein essential for nuclear disassembly in apoptotic cells. AIF / Apoptosis Inducing Factor is found in the mitochondrial intermembrane space, but translocates to the nucleus where it affects chromosome condensation and fragmentation. AIF / Apoptosis Inducing Factor induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in AIF / Apoptosis Inducing Factor cause combined oxidative phosphorylation deficiency 6 (COXPD6), and X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4).

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