Human AGR3 Recombinant Protein (RPPB2716)
- SKU:
- RPPB2716
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8TD06
Description
| Product Name: | Human AGR3 Recombinant Protein |
| Product Code: | RPPB2716 |
| Size: | 20µg |
| Species: | Human |
| Target: | AGR3 |
| Synonyms: | Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11, UNQ642/PRO1272, HAG3, PDIA18. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | AGR3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMIAIKKE KRPPQTLSRG WGDDITWVQT YEEGLFYAQK SKKPLMVIHH LEDCQYSQAL KKVFAQNEEI QEMAQNKFIM LNLMHETTDK NLSPDGQYVP RIMFVDPSLT VRADIAGRYS NRLYTYEPRD LPLLIENMKK ALRLIQSEL |
Anterior gradient protein 3 homolog precursor (AGR3) is a secreted cytoplasmic protein that is involved in metastasis induction and p53 tumor suppressor inhibition. AGR3 may function as molecular marker and potential therapeutic target for hormone-responsive breast tumors.
AGR3 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids (22-166 a.a) and having a molecular mass of 19.5kDa.AGR3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | AGR3: Belongs to the AGR family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 7p21.1Cellular Component: extracellular regionMolecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TD06 |
| NCBI GenInfo Identifier: | 28827801 |
| NCBI Gene ID: | 155465 |
| NCBI Accession: | NP_789783.1 |
| UniProt Secondary Accession: | Q8TD06,A4D120 |
| UniProt Related Accession: | Q8TD06 |
| Molecular Weight: | 19,171 Da |
| NCBI Full Name: | anterior gradient protein 3 homolog |
| NCBI Synonym Full Names: | anterior gradient 3 homolog (Xenopus laevis) |
| NCBI Official Symbol: | AGR3�� |
| NCBI Official Synonym Symbols: | AG3; HAG3; hAG-3; BCMP11; PDIA18�� |
| NCBI Protein Information: | anterior gradient protein 3 homolog; AG-3; anterior gradient homolog 3; breast cancer membrane protein 11; protein disulfide isomerase family A, member 18 |
| UniProt Protein Name: | Anterior gradient protein 3 homolog |
| UniProt Synonym Protein Names: | Breast cancer membrane protein 11 |
| Protein Family: | Anterior gradient protein |
| UniProt Gene Name: | AGR3�� |
| UniProt Entry Name: | AGR3_HUMAN |
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