Enzymes Recombinant Proteins

Human ADH1A Recombinant Protein (RPPB5790)

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SKU:
RPPB5790
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P07327
Research Area:
Enzymes

Description

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Product Name:Human ADH1A Recombinant Protein
Product Code:RPPB5790
Size:20µg
Species:Human
Target:ADH1A
Synonyms:Alcohol dehydrogenase 1A, Alcohol dehydrogenase subunit alpha, ADH1A, ADH1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The ADH1A solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MSTAGKVIKC KAAVLWELKK PFSIEEVEVA PPKAHEVRIK MVAVGICGTD DHVVSGTMVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLAIPQCGK CRICKNPESN YCLKNDVSNP QGTLQDGTSR FTCRRKPIHH FLGISTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAIM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPDSQ NLSMNPMLLL TGRTWKGAIL GGFKSKECVP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TILMF

Alcohol dehydrogenase 1A (ADH1A) is a member of the alcohol dehydrogenase family. ADH1A has a key role in ethanol metabolism. ADH1A along with coenzyme NAD catalyzes the reversible conversion of organic alcohols to ketones or aldehydes. The physiologic function of ADH1A in the liver is the elimination of ethanol formed by microorganisms in the intestinal tract. ADH1A is monomorphic and predominant in fetal and infant livers, growing to be less active in gestation and only weakly active during adulthood.

ADH1A Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 395 amino acids (1-375) and having a molecular mass of 42kDa.ADH1A is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Code:P07327
NCBI GenInfo Identifier:4501929
NCBI Gene ID:124
NCBI Accession:NP_000658.1
UniProt Secondary Accession:P07327,Q17R68, A8K3E3,
UniProt Related Accession:P07327
Molecular Weight:375
NCBI Full Name:alcohol dehydrogenase 1A
NCBI Synonym Full Names:alcohol dehydrogenase 1A (class I), alpha polypeptide
NCBI Official Symbol:ADH1A��
NCBI Official Synonym Symbols:ADH1��
NCBI Protein Information:alcohol dehydrogenase 1A; ADH, alpha subunit; aldehyde reductase; alcohol dehydrogenase subunit alpha; alcohol dehydrogenase 1 (class I), alpha polypeptide
UniProt Protein Name:Alcohol dehydrogenase 1A
UniProt Synonym Protein Names:Alcohol dehydrogenase subunit alpha
Protein Family:Alcohol dehydrogenase
UniProt Gene Name:ADH1A��
UniProt Entry Name:ADH1A_HUMAN
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