Enzymes Recombinant Proteins

Human ADH1A Recombinant Protein (RPPB1353)

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SKU:
RPPB1353
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P07327
Research Area:
Enzymes

Description

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Product Name:Human ADH1A Recombinant Protein
Product Code:RPPB1353
Size:10µg
Species:Human
Target:ADH1A
Synonyms:ADH1A, Alcohol dehydrogenase 1A, Alcohol dehydrogenase 1A, Alcohol dehydrogenase subunit alpha, ADH1.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered clear solution.
Formulation:ADH1A protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by analysis by SDS-PAGE.
Amino Acid Sequence:MSTAGKVIKC KAAVLWELKK PFSIEEVEVA PPKAHEVRIK MVAVGICGTD DHVVSGTMVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLAIPQCGK CRICKNPESN YCLKNDVSNP QGTLQDGTSR FTCRRKPIHH FLGISTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAIM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPDSQ NLSMNPMLLL TGRTWKGAIL GGFKSKECVP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TILMFHHHHH H

Alcohol dehydrogenase 1A (ADH1A) is a member of the alcohol dehydrogenase family. ADH1A has a key role in ethanol metabolism. ADH1A along with coenzyme NAD catalyzes the reversible conversion of organic alcohols to ketones or aldehydes. The physiologic function of ADH1A in the liver is the elimination of ethanol formed by microorganisms in the intestinal tract. ADH1A is monomorphic and predominant in fetal and infant livers, growing to be less active in gestation and only weakly active during adulthood.

ADH1A Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 381 amino acids (1-375) and having a molecular mass of 40.6kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).ADH1A is fused to a 6 amino acid IgG His-Tag at C-terminus and purified by proprietary chromatographic techniques.

UniProt Code:P07327
NCBI GenInfo Identifier:4501929
NCBI Gene ID:124
NCBI Accession:NP_000658.1
UniProt Secondary Accession:P07327,Q17R68, A8K3E3,
UniProt Related Accession:P07327
Molecular Weight:375
NCBI Full Name:alcohol dehydrogenase 1A
NCBI Synonym Full Names:alcohol dehydrogenase 1A (class I), alpha polypeptide
NCBI Official Symbol:ADH1A��
NCBI Official Synonym Symbols:ADH1��
NCBI Protein Information:alcohol dehydrogenase 1A; ADH, alpha subunit; aldehyde reductase; alcohol dehydrogenase subunit alpha; alcohol dehydrogenase 1 (class I), alpha polypeptide
UniProt Protein Name:Alcohol dehydrogenase 1A
UniProt Synonym Protein Names:Alcohol dehydrogenase subunit alpha
Protein Family:Alcohol dehydrogenase
UniProt Gene Name:ADH1A��
UniProt Entry Name:ADH1A_HUMAN
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