Enzymes Recombinant Proteins

Human ADAL Recombinant Protein (RPPB5788)

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SKU:
RPPB5788
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q6DHV7
Research Area:
Enzymes

Description

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Product Name:Human ADAL Recombinant Protein
Product Code:RPPB5788
Size:20µg
Species:Human
Target:ADAL
Synonyms:Adenosine Deaminase-Like, Adenosine Deaminase-Like Protein, EC 3.5.4.-, EC 3.5.4, ADAL.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The ADAL solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity:Greater than 80% as determined by Analysis by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSEFMIEAE EQQPCKTDFY SELPKVELHA HLNGSISSHT MKKLIAQKPD LKIHDQMTVI DKGKKRTLEE CFQMFQTIHQ LTSSPEDILM VTKDVIKEFA DDGVKYLELR STPRRENATG MTKKTYVESI LEGIKQSKQE NLDIDVRYLI AVDRRGGPLV AKETVKLAEE FFLSTEGTVL GLDLSGDPTV GQAKDFLEPL LEAKKAGLKL ALHLSEIPNQ KKETQILLDL LPDRIGHGTF LNSGEGGSLD LVDFVRQHRI PLGKAWSFRS SR

Adenosine deaminase-like protein (ADAL) is a putative nucleoside deaminase. ADAL catalyzes the hydrolytic deamination of adenosine or some similar substrate and has a role in purine metabolism.

ADAL Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 292 amino acids (1-267) and having a molecular mass of 32.7kDa.ADAL is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ADAL: Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism. Belongs to the adenosine and AMP deaminases family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Hydrolase; EC 3.5.4.-

Chromosomal Location of Human Ortholog: 15q15.3

Cellular Component: cytosol

Molecular Function:adenosine deaminase activity

Biological Process: adenosine catabolic process; drug metabolic process; hypoxanthine salvage; inosine biosynthetic process; purine salvage

UniProt Code:Q6DHV7
NCBI GenInfo Identifier:146286026
NCBI Gene ID:161823
NCBI Accession:Q6DHV7.2
UniProt Secondary Accession:Q6DHV7,A6NHZ3, B4DQM8,
UniProt Related Accession:Q6DHV7
Molecular Weight:37,362 Da
NCBI Full Name:Adenosine deaminase-like protein
NCBI Synonym Full Names:adenosine deaminase like
NCBI Official Symbol:ADAL��
NCBI Protein Information:adenosine deaminase-like protein
UniProt Protein Name:Adenosine deaminase-like protein
UniProt Gene Name:ADAL��
UniProt Entry Name:ADAL_HUMAN
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