Human ACBD6 Recombinant Protein (RPPB2697)

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SKU:
RPPB2697
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9BR61

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human ACBD6 Recombinant Protein
Product Code:RPPB2697
Size:20µg
Species:Human
Target:ACBD6
Synonyms:Acyl-CoA Binding Domain Containing 6, Acyl-Coenzyme ABinding Domain Containing 6, Acyl-CoA-Binding Domain-Containing Protein 6, ACBD6.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:ACBD6 protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMASSFLP AGAITGDSGG ELSSGDDSGE VEFPHSPEIE ETSCLAELFE KAAAHLQGLI QVASREQLLY LYARYKQVKV GNCNTPKPSF FDFEGKQKWE AWKALGDSSP SQAMQEYIAV VKKLDPGWNP QIPEKKGKEA NTGFGGPVIS SLYHEETIRE EDKNIFDYCR ENNIDHITKA IKSKNVDVNV KDEEGRALLH WACDRGHKEL VTVLLQHRAD INCQDNEGQT ALHYASACEF LDIVELLLQS GADPTLRDQD GCLPEEVTGC KTVSLVLQRH TTGKA

Acyl-CoAbinding domain containing 6, also known as ACBD6 contains 1 ACB(acyl-CoA-binding) domain and 2 ANK repeats. ACBD6 binds long-chainacyl-coenzyme A molecules with a strong preference for unsaturated C18:1 CoA,lower affinity for unsaturated C20:4-CoA, and extremely weak affinity forsaturated C16:0-CoA. Moreover ACBD6 doesnot bind fatty acids. ACBD6 has been detected in placenta, umbilical cordblood, CD34-positive hematopoietic progenitor cells and bone marrow.Endotheliitis has been associated with ACBD6.

ACBD6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 305 amino acids (1-282aa) and having a molecular mass of 33.5kDa.ACBD6 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ACBD6: Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0- CoA. Does not bind fatty acids.
UniProt Protein Details:

Protein type:Lipid-binding

Chromosomal Location of Human Ortholog: 1q25.3

Cellular Component: cytoplasm

Molecular Function:acyl-CoA binding; lipid binding

UniProt Code:Q9BR61
NCBI GenInfo Identifier:74762703
NCBI Gene ID:84320
NCBI Accession:Q9BR61.1
UniProt Secondary Accession:Q9BR61,Q9D061, Q5RJK8,
UniProt Related Accession:Q9BR61
Molecular Weight:31,151 Da
NCBI Full Name:Acyl-CoA-binding domain-containing protein 6
NCBI Synonym Full Names:acyl-CoA binding domain containing 6
NCBI Official Symbol:ACBD6��
NCBI Protein Information:acyl-CoA-binding domain-containing protein 6
UniProt Protein Name:Acyl-CoA-binding domain-containing protein 6
Protein Family:Acyl-CoA-binding domain-containing protein
UniProt Gene Name:ACBD6��
UniProt Entry Name:ACBD6_HUMAN
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system_update_altDatasheetHuman ACBD6 Recombinant Protein Acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus