Enzymes Recombinant Proteins

Human ABHD14B Recombinant Protein (RPPB5763)

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SKU:
RPPB5763
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q96IU4
Research Area:
Enzymes

Description

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Product Name:Human ABHD14B Recombinant Protein
Product Code:RPPB5763
Size:5µg
Species:Human
Target:ABHD14B
Synonyms:Abhydrolase domain containing protein 14B, CIB, CCG1-interacting factor B, cell cycle gene 1-interacting factor B, EC 3.1.11.6, EC 3.1.21.4.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The ABHD14B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl, 1mM DTT and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMAASVE QREGTIQVQG QALFFREALP GSGQARFSVL LLHGIRFSSE TWQNLGTLHR LAQAGYRAVA IDLPGLGHSK EAAAPAPIGE LAPGSFLAAV VDALELGPPV VISPSLSGMY SLPFLTAPGS QLPGFVPVAP ICTDKINAAN YASVKTPALI VYGDQDPMGQ TSFEHLKQLP NHRVLIMKGA GHPCYLDKPE EWHTGLLDFL QGLQ

ABHD14B is a member of the AB hydrolase superfamily. ABHD14B has an alpha/beta hydrolase fold - a catalytic domain found in a large number of enzymes. In molecular biology, the alpha/beta hydrolase fold is common to a number of hydrolytic enzymes of broad differing phylogenetic source and catalytic function. The Ab hydrolase domain containing gene subfamily includes 15 mostly uncharacterized members. ABHD14B has hydrolase activity with p-nitrophenyl butyrate (in vitro) and is able to activate transcription.

ABHD14B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 234 amino acids (1-210) and having a molecular mass of 25.0kDa.ABHD14B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ABHD14B: Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription. Belongs to the AB hydrolase superfamily. ABHD14 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.-.-.-; Hydrolase

Chromosomal Location of Human Ortholog: 3p21.2

Cellular Component: cytoplasm; nucleolus; cytosol; nucleus

Molecular Function:protein binding; hydrolase activity

Biological Process: metabolic process; positive regulation of transcription from RNA polymerase II promoter

UniProt Code:Q96IU4
NCBI GenInfo Identifier:34222621
NCBI Gene ID:84836
NCBI Accession:Q96IU4.1
UniProt Secondary Accession:Q96IU4,Q86VK8, Q8N8W5,
UniProt Related Accession:Q96IU4
Molecular Weight:210
NCBI Full Name:Alpha/beta hydrolase domain-containing protein 14B
NCBI Synonym Full Names:abhydrolase domain containing 14B
NCBI Official Symbol:ABHD14B��
NCBI Official Synonym Symbols:CIB; HEL-S-299��
NCBI Protein Information:alpha/beta hydrolase domain-containing protein 14B; CCG1-interacting factor B; epididymis secretory protein Li 299; cell cycle gene 1-interacting factor B; abhydrolase domain-containing protein 14B
UniProt Protein Name:Alpha/beta hydrolase domain-containing protein 14B
UniProt Synonym Protein Names:CCG1-interacting factor B
Protein Family:Protein
UniProt Gene Name:ABHD14B��
UniProt Entry Name:ABHEB_HUMAN
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