Enzymes Recombinant Proteins
Human ABHD10 Recombinant Protein (RPPB5762)
- SKU:
- RPPB5762
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NUJ1
- Research Area:
- Enzymes
Description
| Product Name: | Human ABHD10 Recombinant Protein |
| Product Code: | RPPB5762 |
| Size: | 10µg |
| Species: | Human |
| Target: | ABHD10 |
| Synonyms: | Abhydrolase domain containing 10 mitochondrial2, FLJ11342, EC 3.4.-.-. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The ABHD10 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 100mM NaCl and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMTSLSF LNRPDLPNLA YKKLKGKSPG IIFIPGYLSY MNGTKALAIE EFCKSLGHAC IRFDYSGVGS SDGNSEESTL GKWRKDVLSI IDDLADGPQI LVGSSLGGWL MLHAAIARPE KVVALIGVAT AADTLVTKFN QLPVELKKEV EMKGVWSMPS KYSEEGVYNV QYSFIKEAEH HCLLHSPIPV NCPIRLLHGM KDDIVPWHTS MQVADRVLST DVDVILRKHS DHRMREKADI QLLVYTIDDL IDKLSTIVN |
Abhydrolase domain-containing protein 10 (ABHD10) is a member of the AB hydrolase superfamily.
ABHD10 Human Recombinant produced in�E. coli is a single polypeptide chain containing 279 amino acids (53-306) and having a molecular mass of 30.9kDa.ABHD10 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a mitochondrially-localized enzyme that acts in liver cells as a hydrolase. The encoded protein removes glucuronide from mycophenolic acid acyl-glucuronide. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] |
| UniProt Code: | Q9NUJ1 |
| NCBI GenInfo Identifier: | 440918682 |
| NCBI Gene ID: | 55347 |
| NCBI Accession: | NP_001258998.1 |
| UniProt Secondary Accession: | Q9NUJ1,Q8TCF9, B7Z6A8, C9IZX5, D3DN63 |
| UniProt Related Accession: | Q9NUJ1 |
| Molecular Weight: | 33 |
| NCBI Full Name: | mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform 2 |
| NCBI Synonym Full Names: | abhydrolase domain containing 10 |
| NCBI Official Symbol: | ABHD10�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | mycophenolic acid acyl-glucuronide esterase, mitochondrial |
| UniProt Protein Name: | Mycophenolic acid acyl-glucuronide esterase, mitochondrial |
| UniProt Synonym Protein Names: | Alpha/beta hydrolase domain-containing protein 10; Abhydrolase domain-containing protein 10 |
| Protein Family: | |
| UniProt Gene Name: | ABHD10�� |
| UniProt Entry Name: |