Human ABCA1 / ATP-binding cassette sub-family A member 1 ELISA Kit

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SKU:
HUFI01146
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O95477
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
ABCA1, ATP-binding cassette transporter A1, ABC1, CERP, HDLDT1, TGD, ABC-1, ATP-binding cassette 1, ATP-binding cassette transporter 1, ATP-binding cassette, sub-family A, member 1, Cholesterol efflux regulatory protein, membrane-bound, TGDATP-bindin
Reactivity:
Human
Research Area:
Metabolism

Description

Human ABCA1 / ATP-binding cassette sub-family A member 1 ELISA Kit

ABCA1 is membrane-associated protein that belongs to the ATP-binding cassette (ABC) transporter superfamily. Various molecules are transported across extracellular and intracellular membranes by ABC proteins. ABC genes are classified into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. The ABC1 subfamily is the only major ABC subfamily that is only found in multicellular eukaryotes. ABCA1 acts as a cholesteral efflux pump in the cellular lipid removal pathway. Tangier disease and familial high-density lipoprotein (HDL) deficiency are caused by mutations in both alleles of ABCA1.Tangier Disease and Primary Hypoalphalipoproteinemia are two diseases linked to ABCA1. SREBF and miR33 in cholesterol and lipid homeostasis, as well as Folate Metabolism, are related pathways to ABCA1.

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