Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells; but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL; and possibly active during T cell activation.
Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.03µg/ml(100 ?l/well) can bind Human 4-1BB-Fc. The ED50 of Human 4-1BB-Fc is 7.22 ug/ml .
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a Fc; 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
44.0 kDa
AP Mol Mass:
55-75 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_altDatasheetHuman 4BB/TNFRSF9 Recombinant Protein Tumor necrosis factor receptor superfamily member 9(TNFRSF9); also known as CD137 and 4-1BB; is an inducible T cell surface protein
system_update_altDatasheetHuman 4BB/TNFRSF9 Recombinant Protein Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor s
system_update_altDatasheetHuman 4BB/TNFRSF9 Recombinant Protein Tumor necrosis factor receptor superfamily member 9(TNFRSF9); also known as CD137 and 4-1BB; is an inducible T cell surface protein
system_update_altDatasheetMouse 4BB/TNFRSF9 Recombinant Protein CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, wh
system_update_altDatasheetMouse 4BB/TNFRSF9 Recombinant Protein Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can
system_update_altDatasheetCynomolgus 4BB/TNFRSF9/CD137 Recombinant Protein Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surf
system_update_altDatasheetCynomolgus 4BB/TNFRSF9/CD137 Recombinant Protein Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surf