Immune Checkpoint Recombinant Proteins

Human 4-1BB Recombinant Protein (mFc-His Tag) (HDPT0011)

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SKU:: HDPT0011
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Human
Research Area:: Immune Checkpoint

Description
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Description

Human 4-1BB Recombinant Protein (mFc-His Tag)

Description:	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Product name:	Human 4-1BB Recombinant Protein (mFc-His Tag)
Synonyms:	TNFRSF9, 4-1BB, CD137, CDw137, ILA
Type:	protein
Size:	50 µg
Name:	4-1BB
Origin:	Human
Source:	HEK293
Protein Type:	Recombinant
Application:	Flow Cyt
Purity:	> 95%
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C-Mouse Fc and 6×His tag
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	41BB（Leu24-Gln186）+mFc（Pro99-Lys330）+6×His
Gene ID:	3604
Uniprot:	Q07011
Molecular Weight:	54-60 kDa