Description
Antibody Name: | HTR3E Antibody (PACO64083) |
Antibody SKU: | PACO64083 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human 5-hydroxytryptamine receptor 3E protein (26-248AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Antigen Affinity purified & Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate, Rat Heart tissue, Mouse Heart tissue. All lanes: HTR3E antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52, 50, 53, 51, 54 kDa. Observed band size: 50 kDa. |
Background: | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. |
Synonyms: | 5-hydroxytryptamine receptor 3E (5-HT3-E) (5-HT3E) (Serotonin receptor 3E), HTR3E |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2012] |
UniProt Code: | A5X5Y0 |
NCBI GenInfo Identifier: | 162416113 |
NCBI Gene ID: | 285242 |
NCBI Accession: | A5X5Y0.1 |
UniProt Secondary Accession: | A5X5Y0 |
UniProt Related Accession: | A5X5Y0 |
Molecular Weight: | 53kDa |
NCBI Full Name: | 5-hydroxytryptamine receptor 3E |
NCBI Synonym Full Names: | 5-hydroxytryptamine receptor 3E |
NCBI Official Symbol: | HTR3E |
NCBI Official Synonym Symbols: | 5-HT3E; 5-HT3-E; 5-HT3c1 |
NCBI Protein Information: | 5-hydroxytryptamine receptor 3E |
UniProt Protein Name: | |
UniProt Synonym Protein Names: | |
Protein Family: | 5-hydroxytryptamine receptor |
UniProt Gene Name: | |
UniProt Entry Name: |