HTR3D Antibody (PACO36858)
- SKU:
- PACO36858
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HTR3D Antibody (PACO36858) |
| Antibody SKU: | PACO36858 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 5-hydroxytryptamine receptor 3D protein (107-210AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: HTR3D antibody at 2µg/ml + Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51, 31, 26, 46 kDa. Observed band size: 51 kDa. |
 | Immunofluorescent analysis of Hela cells using PACO36858 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. |
| Synonyms: | 5-hydroxytryptamine receptor 3D (5-HT3-D) (5-HT3D) (Serotonin receptor 3D), HTR3D |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] |
| UniProt Code: | Q70Z44 |
| NCBI GenInfo Identifier: | 223468705 |
| NCBI Gene ID: | 200909 |
| NCBI Accession: | NP_001138615.1 |
| UniProt Secondary Accession: | Q70Z44 |
| UniProt Related Accession: | Q70Z44 |
| Molecular Weight: | |
| NCBI Full Name: | 5-hydroxytryptamine receptor 3D isoform 1 |
| NCBI Synonym Full Names: | 5-hydroxytryptamine receptor 3D |
| NCBI Official Symbol: | HTR3D |
| NCBI Official Synonym Symbols: | 5HT3D |
| NCBI Protein Information: | 5-hydroxytryptamine receptor 3D |
| UniProt Protein Name: | 5-hydroxytryptamine receptor 3D |
| UniProt Synonym Protein Names: | Serotonin receptor 3D |
| Protein Family: | |
| UniProt Gene Name: | HTR3D |
| UniProt Entry Name: | 5HT3D_HUMAN |
| Antibodies |
| HTR3D Antibody (PACO02643) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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