HTR1E Antibody (PACO27465)
- SKU:
- PACO27465
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HTR1E Antibody (PACO27465) |
| Antibody SKU: | PACO27465 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 5-hydroxytryptamine receptor 1E protein (203-291AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: HTR1E antibody at 3.3µg/ml + Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 42 kDa Observed band size: 42 kDa . |
 | Immunohistochemistry analysis of human lung cancer using PACO27465 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO27465 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. |
| Synonyms: | 5-hydroxytryptamine receptor 1E (5-HT-1E) (5-HT1E) (S31) (Serotonin receptor 1E), HTR1E |
| UniProt Protein Function: | 5-HT(1E): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-passChromosomal Location of Human Ortholog: 6q14-q15Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; protein binding; serotonin binding; serotonin receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cyclic nucleotide second messenger |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P28566 |
| NCBI GenInfo Identifier: | 112822 |
| NCBI Gene ID: | 3354 |
| NCBI Accession: | P28566.1 |
| UniProt Secondary Accession: | P28566,Q9P1Y1, E1P503 |
| UniProt Related Accession: | P28566 |
| Molecular Weight: | 41,682 Da |
| NCBI Full Name: | 5-hydroxytryptamine receptor 1E |
| NCBI Synonym Full Names: | 5-hydroxytryptamine receptor 1E |
| NCBI Official Symbol: | HTR1E |
| NCBI Official Synonym Symbols: | 5-HT1E |
| NCBI Protein Information: | 5-hydroxytryptamine receptor 1E |
| UniProt Protein Name: | 5-hydroxytryptamine receptor 1E |
| UniProt Synonym Protein Names: | S31; Serotonin receptor 1E |
| Protein Family: | 5-hydroxytryptamine receptor |
| UniProt Gene Name: | HTR1E |
| UniProt Entry Name: | 5HT1E_HUMAN |
| Antibodies |
| HTR1E Antibody (PACO01534) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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