Name: Hspa5 Antibody (PACO45918)
SKU: PACO45918
Availability: OutOfStock

Antibody Name:	Hspa5 Antibody (PACO45918)
Antibody SKU:	PACO45918
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:	Mouse, Rat
Immunogen:	Recombinant Mouse Endoplasmic reticulum chaperone BiP protein (20-655AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western Blot. Positive WB detected in: Rat liver tissue, Rat brain tissue, Mouse brain tissue. All lanes: Hspa5 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 73 kDa. Observed band size: 73 kDa..
	Immunofluorescent analysis of HepG2 cells using PACO45918 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Background:	Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate (By similarity).
Synonyms:	Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein), Hspa5, Grp78

UniProt Protein Function:	Plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum (PubMed:12475965). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate (PubMed:12411443).
UniProt Code:	P20029
NCBI GenInfo Identifier:	2506545
NCBI Gene ID:	14828
NCBI Accession:	P20029.3
UniProt Related Accession:	P20029
Molecular Weight:
NCBI Full Name:	Endoplasmic reticulum chaperone BiP
NCBI Synonym Full Names:	heat shock protein 5
NCBI Official Symbol:	Hspa5
NCBI Official Synonym Symbols:	Bip; Sez7; mBiP; Grp78; SEZ-7; Hsce70; baffled; AL022860; AU019543; D2Wsu17e; D2Wsu141e
NCBI Protein Information:	endoplasmic reticulum chaperone BiP
UniProt Protein Name:	78 kDa glucose-regulated protein
UniProt Synonym Protein Names:	Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein
UniProt Gene Name:	Hspa5