HSP70 Monoclonal Antibody (CAB21180)
- SKU:
- CAB21180
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | HSP70 Monoclonal Antibody |
| Product Code: | CAB21180 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53087 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, HeLa, Mouse brain, Rat liver, C6 |
| Cellular Location: | blood microparticle, centriole, centrosome, cytoplasm, cytosol, endoplasmic reticulum, extracellular exosome, extracellular region, focal adhesion, mitochondrion, nuclear speck, nucleoplasm, nucleus, perinuclear region of cytoplasm, plasma membrane |
| Customer Validation: | (293T、HeLa、MKW45、HT29、A549) |
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human HSP70 (NP_005336.3). |
| Sequence: | KITIT NDKGR LSKEE IERMV QEAEK YKAED EVQRE RVSAK NALES YAFNM KSAVE DEGLK GKISE ADKKK VLDKC QEVIS WLDAN TLAEK DEFEH KRKEL E |
| Synonyms: | HEL-S-103, HSP70-1, HSP70-1A, HSP70.1, HSP70I, HSP72, HSPA1 |
| Calculated MW: | 70kDa |
| Observed MW: | 70kDa |
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