HS3ST1 Antibody (PACO09802)
- SKU:
- PACO09802
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HS3ST1 Antibody (PACO09802) |
| Antibody SKU: | PACO09802 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human HS3ST1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | heparan sulfate (glucosamine) 3-O-sulfotransferase 1;HS3ST1;3OST;3OST1 ; |
| UniProt Protein Function: | HS3ST1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. Belongs to the sulfotransferase 1 family.Protein type: EC 2.8.2.23; Transferase; Glycan Metabolism - heparan sulfate biosynthesisChromosomal Location of Human Ortholog: 4p16Cellular Component: Golgi lumen; integral to membraneMolecular Function: sulfotransferase activity; heparin-glucosamine 3-O-sulfotransferase activityBiological Process: glycosaminoglycan biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14792 |
| NCBI GenInfo Identifier: | 4826764 |
| NCBI Gene ID: | 9957 |
| NCBI Accession: | NP_005105.1 |
| UniProt Secondary Accession: | O14792,Q6PEY8, B3KUA6 |
| UniProt Related Accession: | O14792 |
| Molecular Weight: | 35,773 Da |
| NCBI Full Name: | heparan sulfate glucosamine 3-O-sulfotransferase 1 |
| NCBI Synonym Full Names: | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| NCBI Official Symbol: | HS3ST1 |
| NCBI Official Synonym Symbols: | 3OST; 3OST1 |
| NCBI Protein Information: | heparan sulfate glucosamine 3-O-sulfotransferase 1; 3-OST-1; h3-OST-1; heparan sulfate 3-O-sulfotransferase 1; heparin-glucosamine 3-O-sulfotransferase; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1 |
| UniProt Protein Name: | Heparan sulfate glucosamine 3-O-sulfotransferase 1 |
| UniProt Synonym Protein Names: | Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; 3-OST-1; Heparan sulfate 3-O-sulfotransferase 1; h3-OST-1 |
| Protein Family: | |
| UniProt Gene Name: | HS3ST1 |
| UniProt Entry Name: | HS3S1_HUMAN |
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