Description
Antibody Name: | Hpx Antibody (PACO27441) |
Antibody SKU: | PACO27441 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Rat, Human |
Immunogen: | Recombinant Rat Hemopexin protein (24-460AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: Hpx antibody at 4.5µg/ml + HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa . |
Background: | Binds heme and transports it to the liver for breakdown and iron recovery,after which the free hemopexin returns to the circulation. |
Synonyms: | Hemopexin, Hpx |
UniProt Protein Function: | HPX: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Belongs to the hemopexin family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 1q32 Cellular Component: cell; extracellular space Molecular Function:heme transporter activity; metal ion binding Biological Process: cellular iron ion homeostasis; heme metabolic process; heme transport; hemoglobin metabolic process; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of immunoglobulin production; positive regulation of tyrosine phosphorylation of STAT protein; regulation of protein metabolic process |
NCBI Summary: | a heme binding globulin protein [RGD, Feb 2006] |
UniProt Code: | P20059 |
NCBI GenInfo Identifier: | 16758014 |
NCBI Gene ID: | 58917 |
NCBI Accession: | NP_445770.1 |
UniProt Secondary Accession: | P20059,Q5BKB4, |
UniProt Related Accession: | P20059 |
Molecular Weight: | 51,351 Da |
NCBI Full Name: | hemopexin |
NCBI Synonym Full Names: | hemopexin |
NCBI Official Symbol: | Hpx |
NCBI Official Synonym Symbols: | Hpxn |
NCBI Protein Information: | hemopexin |
UniProt Protein Name: | Hemopexin |
Protein Family: | Hemopexin |
UniProt Gene Name: | Hpx |