HPRT1 Polyclonal Antibody
- SKU:
- CAB21825
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | HPRT1 Polyclonal Antibody |
| Product Code: | CAB21825 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | C6, Mouse brain, Rat heart |
| Cellular Location: | Cytoplasm |
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human HPRT1 (NP_000185.1). |
| Sequence: | MATRS PGVVI SDDEP GYDLD LFCIP NHYAE DLERV FIPHG LIMDR TERLA RDVMK EMGGH HIVAL CVLKG GYKFF ADLLD YIKAL NRNSD RSIPM TVDFI RLKSY CNDQS TGDIK VIGGD DLSTL TGKNV LIVED IIDTG KTMQT LLSLV RQYNP KMVKV ASLLV KRTPR SVGYK PDFVG FEIPD KFVVG YALDY NEYFR DLNHV CVISE TGKAK YKA |
| Synonyms: | HPRT, HGPRT |
| Calculated MW: | 25kDa |
| Observed MW: | 25kDa |
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