Description
Antibody Name: | HOXD11 Antibody (PACO18080) |
Antibody SKU: | PACO18080 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:1000-1:3000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human HOXD11 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10+12%SDS-PAGE, Lysate: 30 μg, Lane: Mouse kidney tissue, Primary antibody: PACO18080(HOXD11 Antibody) at dilution 1/1100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 60 seconds. |
Background: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis. |
Synonyms: | homeobox D11 |
UniProt Protein Function: | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
NCBI Summary: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P31277 |
NCBI GenInfo Identifier: | 223590220 |
NCBI Gene ID: | 3237 |
NCBI Accession: | P31277.3 |
UniProt Related Accession: | P31277 |
Molecular Weight: | |
NCBI Full Name: | Homeobox protein Hox-D11 |
NCBI Synonym Full Names: | homeobox D11 |
NCBI Official Symbol: | HOXD11 |
NCBI Official Synonym Symbols: | HOX4; HOX4F |
NCBI Protein Information: | homeobox protein Hox-D11 |
UniProt Protein Name: | Homeobox protein Hox-D11 |
UniProt Synonym Protein Names: | Homeobox protein Hox-4F |
UniProt Gene Name: | HOXD11 |
UniProt Entry Name: | HXD11_HUMAN |