HOXD10 Monoclonal Antibody
- SKU:
- CAB23992
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | HOXD10 Monoclonal Antibody |
| Product Code: | CAB23992 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62112 |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse kidney |
| Cellular Location: | Nucleus |
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 1-150 of human HOXD10 (NP_002139.2). |
| Sequence: | MSFPN SSPAA NTFLV DSLIS ACRSD SFYSS SASMY MPPPS ADMGT YGMQT CGLLP SLAKR EVNHQ NMGMN VHPYI PQVDS WTDPN RSCRI EQPVT QQVPT CSFTT NIKEE SNCCM YSDKR NKLIS AEVPS YQRLV PESCP VENPE VPVPG |
| Synonyms: | HOX4, HOX4D, HOX4E, Hox-4.4 |
| Calculated MW: | 38kDa |
| Observed MW: | 38kDa |
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