HOXB3 Antibody (PACO59748)
- SKU:
- PACO59748
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HOXB3 Antibody (PACO59748) |
| Antibody SKU: | PACO59748 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:500-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Homeobox protein Hox-B3 protein (315-423AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO59748 diluted at 1:600 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
| Synonyms: | Homeobox protein Hox-B3 (Homeobox protein Hox-2.7) (Homeobox protein Hox-2G), HOXB3, HOX2G |
| UniProt Protein Function: | HOXB3: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 17q21.3Biological Process: angiogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008] |
| UniProt Code: | P14651 |
| NCBI GenInfo Identifier: | 215274007 |
| NCBI Gene ID: | 3213 |
| NCBI Accession: | P14651.2 |
| UniProt Secondary Accession: | P14651,O95615, P17484, A8K567, B7Z5N8, B7Z5P8, B7ZAD0 D3DTV3 |
| UniProt Related Accession: | P14651 |
| Molecular Weight: | 30,989 Da |
| NCBI Full Name: | Homeobox protein Hox-B3 |
| NCBI Synonym Full Names: | homeobox B3 |
| NCBI Official Symbol: | HOXB3 |
| NCBI Official Synonym Symbols: | HOX2; HOX2G; Hox-2.7 |
| NCBI Protein Information: | homeobox protein Hox-B3 |
| UniProt Protein Name: | Homeobox protein Hox-B3 |
| UniProt Synonym Protein Names: | Homeobox protein Hox-2.7; Homeobox protein Hox-2G |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | HOXB3 |
| UniProt Entry Name: | HXB3_HUMAN |
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