HOXA4 Antibody (PACO18078)
- SKU:
- PACO18078
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HOXA4 Antibody (PACO18078) |
| Antibody SKU: | PACO18078 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human HOXA4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18078(HOXA4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18078(HOXA4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation |
| Synonyms: | homeobox A4 |
| UniProt Protein Function: | HOXA4: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT- 3'. Belongs to the Antp homeobox family. Deformed subfamily.Protein type: DNA-binding; Transcription factorChromosomal Location of Human Ortholog: 7p15.2Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activityBiological Process: anterior/posterior pattern formation; anatomical structure morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent; embryonic skeletal morphogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q00056 |
| NCBI GenInfo Identifier: | 116242514 |
| NCBI Gene ID: | 3201 |
| NCBI Accession: | Q00056.3 |
| UniProt Secondary Accession: | Q00056,O43366, A4D180 |
| UniProt Related Accession: | Q00056 |
| Molecular Weight: | 34,499 Da |
| NCBI Full Name: | Homeobox protein Hox-A4 |
| NCBI Synonym Full Names: | homeobox A4 |
| NCBI Official Symbol: | HOXA4 |
| NCBI Official Synonym Symbols: | HOX1; HOX1D |
| NCBI Protein Information: | homeobox protein Hox-A4; homeo box A4; Dfd-like protein; Hox-1.4-like protein; homeobox protein Hox-1D; homeobox protein Hox-1.4 |
| UniProt Protein Name: | Homeobox protein Hox-A4 |
| UniProt Synonym Protein Names: | Homeobox protein Hox-1.4; Homeobox protein Hox-1D |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | HOXA4 |
| UniProt Entry Name: | HXA4_HUMAN |
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