HOMER3 Antibody (PACO09771)
- SKU:
- PACO09771
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HOMER3 Antibody (PACO09771) |
| Antibody SKU: | PACO09771 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human HOMER3 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | homer homolog 3 (Drosophila);HOMER3;HOMER-3;VESL3 ; |
| UniProt Protein Function: | HOMER3: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Belongs to the Homer family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 19p13.11Cellular Component: postsynaptic membrane; cytoplasm; plasma membrane; cell junction; cytosolMolecular Function: protein C-terminus binding; protein domain specific binding; protein binding; metabotropic glutatmate receptor bindingBiological Process: metabotropic glutamate receptor signaling pathway; protein targeting |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] |
| UniProt Code: | Q9NSC5 |
| NCBI GenInfo Identifier: | 38605068 |
| NCBI Gene ID: | 9454 |
| NCBI Accession: | Q9NSC5.2 |
| UniProt Secondary Accession: | Q9NSC5 |
| UniProt Related Accession: | Q9NSC5 |
| Molecular Weight: | |
| NCBI Full Name: | Homer protein homolog 3 |
| NCBI Synonym Full Names: | homer scaffold protein 3 |
| NCBI Official Symbol: | HOMER3 |
| NCBI Official Synonym Symbols: | VESL3; HOMER-3 |
| NCBI Protein Information: | homer protein homolog 3 |
| UniProt Protein Name: | Homer protein homolog 3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Homer protein |
| UniProt Gene Name: | HOMER3 |
| UniProt Entry Name: | HOME3_HUMAN |
Related Products
Human TP53 antibody(p53 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
OSTN Antibody
Overview Product Name:OSTN AntibodyProduct Code:PACO64881Size:50µLTarget Names:OSTNSpecies Reactivity:HumanHost
CYP2A13 Antibody
Overview Product Name:CYP2A13 AntibodyProduct Code:PACO64657Size:50µLTarget Names:CYP2A13Species Reactivity:Human, Mouse