HNF1α Monoclonal Antibody
- SKU:
- CAB22139
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
Description
| Product Name: | HNF1α Monoclonal Antibody |
| Product Code: | CAB22139 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55848 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC-P, ELISA |
| Key Applications: | Immunohistochemistry |
| Recommended Dilution: | IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-128 of human HNF1α (NP_000536.6). |
| Sequence: | GEPGP YLLAG EGPLD KGESC GGGRG ELAEL PNGLG ETRGS EDETD DDGED FTPPI LKELE NLSPE EAAHQ KAVVE TLLQE DPWRV AKMVK SYLQQ HNI |
| Synonyms: | HNF1, LFB1, TCF1, HNF4A, MODY3, TCF-1, HNF-1A, IDDM20, HNF1alpha, HNF-1-alpha |
| Calculated MW: | 67kDa |
| Observed MW: | 81kDa |
Related Products
SPAM1 Monoclonal Antibody
OverviewProduct Name:SPAM1 Monoclonal AntibodyProduct Code:CAB22178Reactivity:Human, Mouse, RatApplications:Western blotting, Imm
PMS2 Monoclonal Antibody
OverviewProduct Name:PMS2 Monoclonal AntibodyProduct Code:CAB22350Reactivity:HumanApplications:Western blotting
ACSL3 Monoclonal Antibody
OverviewProduct Name:ACSL3 Monoclonal AntibodyProduct Code:CAB22085Reactivity:Human, Mouse, RatApplications:Western blotting, Imm
NeuroD1 Monoclonal Antibody
OverviewProduct Name:NeuroD1 Monoclonal AntibodyProduct Code:CAB12020Reactivity:MouseApplications:Western blotting<
PRPF4 Monoclonal Antibody
OverviewProduct Name:PRPF4 Monoclonal AntibodyProduct Code:CAB21132Reactivity:Human, Mouse, RatApplications:Western blotting, Imm
UCP1 Monoclonal Antibody
OverviewProduct Name:UCP1 Monoclonal AntibodyProduct Code:CAB21979Reactivity:MouseApplications:Western blotting
Filamin A Monoclonal Antibody
Filamin A Monoclonal AntibodyThe product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!
IRP2 Monoclonal Antibody
OverviewProduct Name:IRP2 Monoclonal AntibodyProduct Code:CAB22283Reactivity:Human, Mouse, RatApplications:Western blotting, Immu
PLCB2 Monoclonal Antibody
OverviewProduct Name:PLCB2 Monoclonal AntibodyProduct Code:CAB22526Reactivity:Human, MouseApplications:Western blotting, Immunohi