Description
| Antibody Name: | HMGXB4 Antibody (PACO62103) |
| Antibody SKU: | PACO62103 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Peptide sequence from Human HMG domain-containing protein 4 protein (489-509AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Jurkat whole cell lysate, K562 whole cell lysate. All lanes: HMGXB4 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 66 kDa. Observed band size: 66 kDa. |
| Background: | Negatively regulates Wnt/beta-catenin signaling during development. |
| Synonyms: | HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG), HMGXB4, HMG2L1 HMGBCG |
| UniProt Protein Function: | HMG2L1: Negatively regulates Wnt/beta-catenin signaling during development.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 22q13.1Molecular Function: DNA binding; chromatin bindingBiological Process: chromatin remodeling; negative regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; endosome to lysosome transport |
| UniProt Protein Details: | |
| NCBI Summary: | High mobility group (HMG) proteins are nonhistone chromosomal proteins. See HMG2 (MIM 163906) for additional information on HMG proteins.[supplied by OMIM, Nov 2010] |
| UniProt Code: | Q9UGU5 |
| NCBI GenInfo Identifier: | 51173873 |
| NCBI Gene ID: | 10042 |
| NCBI Accession: | NP_001003681.1 |
| UniProt Secondary Accession: | Q9UGU5,O75672, O75673, Q9UMT5 |
| UniProt Related Accession: | Q9UGU5 |
| Molecular Weight: | 65,712 Da |
| NCBI Full Name: | HMG domain-containing protein 4 |
| NCBI Synonym Full Names: | HMG box domain containing 4 |
| NCBI Official Symbol: | HMGXB4 |
| NCBI Official Synonym Symbols: | HMG2L1; HMGBCG; THC211630 |
| NCBI Protein Information: | HMG domain-containing protein 4; HMG box-containing protein 4; high mobility group protein 2-like 1; high-mobility group protein 2-like 1 |
| UniProt Protein Name: | HMG domain-containing protein 4 |
| UniProt Synonym Protein Names: | HMG box-containing protein 4; High mobility group protein 2-like 1; Protein HMGBCG |
| Protein Family: | HMG box-containing protein |
| UniProt Gene Name: | HMGXB4 |
| UniProt Entry Name: | HMGX4_HUMAN |
