HMGN5 Antibody (PACO18784)
- SKU:
- PACO18784
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HMGN5 Antibody (PACO18784) |
| Antibody SKU: | PACO18784 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human HMGN5 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO18784(HMGN5 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. |
| Synonyms: | High mobility group nucleosome binding domain 5 |
| UniProt Protein Function: | NSBP1: Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. Belongs to the HMGN family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: Xq13.3 Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus Molecular Function:chromatin binding Biological Process: negative regulation of apoptosis; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009] |
| UniProt Code: | P82970 |
| NCBI GenInfo Identifier: | 23396771 |
| NCBI Gene ID: | 79366 |
| NCBI Accession: | P82970.1 |
| UniProt Secondary Accession: | P82970,Q5JSL1, |
| UniProt Related Accession: | P82970 |
| Molecular Weight: | 31,525 Da |
| NCBI Full Name: | High mobility group nucleosome-binding domain-containing protein 5 |
| NCBI Synonym Full Names: | high mobility group nucleosome binding domain 5 |
| NCBI Official Symbol: | HMGN5 |
| NCBI Official Synonym Symbols: | NSBP1; NBP-45 |
| NCBI Protein Information: | high mobility group nucleosome-binding domain-containing protein 5 |
| UniProt Protein Name: | High mobility group nucleosome-binding domain-containing protein 5 |
| UniProt Synonym Protein Names: | Nucleosome-binding protein 1 |
| Protein Family: | High mobility group nucleosome-binding domain-containing protein |
| UniProt Gene Name: | HMGN5 |
| UniProt Entry Name: | HMGN5_HUMAN |
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