Hmgcs1 Antibody (PACO37766)

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SKU:
PACO37766
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Applications:
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated

Description

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Antibody Name:Hmgcs1 Antibody (PACO37766)
Antibody SKU:PACO37766
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:Mouse
Immunogen:Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, cytoplasmic protein (1-520AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern blot. All lanes: Hmgcs1 antibody at 12µg/ml. Lane 1: NIH/3T3 whole cell lysate. Lane 2: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 58 kDa. Observed band size: 58 kDa.
Background:This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Synonyms:Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase), Hmgcs1
UniProt Protein Function:HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - butanoate; EC 2.3.3.10; Lipid Metabolism - synthesis and degradation of ketone bodies; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; TransferaseChromosomal Location of Human Ortholog: 13 D2.3|13Cellular Component: cytoplasm; cytosolMolecular Function: catalytic activity; drug binding; hydroxymethylglutaryl-CoA synthase activity; isomerase activity; organic acid binding; protein homodimerization activity; transferase activityBiological Process: cholesterol biosynthetic process; cholesterol metabolic process; isoprenoid biosynthetic process; lipid metabolic process; metabolic process; response to low density lipoprotein stimulus; response to purine; steroid biosynthetic process; steroid metabolic process; sterol biosynthetic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8JZK9
NCBI GenInfo Identifier:612339316
NCBI Gene ID:208715
NCBI Accession:NP_001278368.1
UniProt Secondary Accession:Q8JZK9,Q3UXI4
UniProt Related Accession:Q8JZK9
Molecular Weight:
NCBI Full Name:hydroxymethylglutaryl-CoA synthase, cytoplasmic
NCBI Synonym Full Names:3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
NCBI Official Symbol:Hmgcs1  
NCBI Official Synonym Symbols:B130032C06Rik  
NCBI Protein Information:hydroxymethylglutaryl-CoA synthase, cytoplasmic
UniProt Protein Name:Hydroxymethylglutaryl-CoA synthase, cytoplasmic
UniProt Synonym Protein Names:3-hydroxy-3-methylglutaryl coenzyme A synthase
Protein Family:
UniProt Gene Name:Hmgcs1  
UniProt Entry Name:
ELISA Kits
Mouse Hydroxymethylglutaryl-CoA synthase, cytoplasmic (Hmgcs1) ELISA Kit
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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