Description
Antibody Name: | Hmgcs1 Antibody (PACO37762) |
Antibody SKU: | PACO37762 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Mouse |
Immunogen: | Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, cytoplasmic protein (1-520AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. |
Synonyms: | Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase), Hmgcs1 |
UniProt Protein Function: | HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - butanoate; EC 2.3.3.10; Lipid Metabolism - synthesis and degradation of ketone bodies; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; TransferaseChromosomal Location of Human Ortholog: 13 D2.3|13Cellular Component: cytoplasm; cytosolMolecular Function: catalytic activity; drug binding; hydroxymethylglutaryl-CoA synthase activity; isomerase activity; organic acid binding; protein homodimerization activity; transferase activityBiological Process: cholesterol biosynthetic process; cholesterol metabolic process; isoprenoid biosynthetic process; lipid metabolic process; metabolic process; response to low density lipoprotein stimulus; response to purine; steroid biosynthetic process; steroid metabolic process; sterol biosynthetic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8JZK9 |
NCBI GenInfo Identifier: | 612339316 |
NCBI Gene ID: | 208715 |
NCBI Accession: | NP_001278368.1 |
UniProt Secondary Accession: | Q8JZK9,Q3UXI4 |
UniProt Related Accession: | Q8JZK9 |
Molecular Weight: | |
NCBI Full Name: | hydroxymethylglutaryl-CoA synthase, cytoplasmic |
NCBI Synonym Full Names: | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 |
NCBI Official Symbol: | Hmgcs1 |
NCBI Official Synonym Symbols: | B130032C06Rik |
NCBI Protein Information: | hydroxymethylglutaryl-CoA synthase, cytoplasmic |
UniProt Protein Name: | Hydroxymethylglutaryl-CoA synthase, cytoplasmic |
UniProt Synonym Protein Names: | 3-hydroxy-3-methylglutaryl coenzyme A synthase |
Protein Family: | |
UniProt Gene Name: | Hmgcs1 |
UniProt Entry Name: |