HMGA2 Monoclonal Antibody
- SKU:
- CAB24392
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | HMGA2 Monoclonal Antibody |
| Product Code: | CAB24392 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63442 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2, Raw264.7 |
| Cellular Location: | Nucleus |
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HMGA2 (NP_003474.1). |
| Sequence: | MSARG EGAGQ PSTSA QGQPA APAPQ KRGRG RPRKQ QQEPT GEPSP KRPRG RPKGS KNKSP SKAAQ KKAEA TGEKR PRGRP RKWPQ QVVQK KPAQE ETEET |
| Synonyms: | BABL, LIPO, SRS5, HMGIC, HMGI-C, STQTL9 |
| Calculated MW: | 12kDa |
| Observed MW: | 18kDa |
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