Description
Product Name: | HIV p24 Recombinant Protein (C-6His) |
Product Code: | RPES7025 |
Size: | 1mg |
Species: | HIV |
Expression Host: | E.coli |
Synonyms: | Capsid protein p24, Human immunodeficiency virus 1, Human immunodeficiency virus type 1 p24 |
Mol Mass: | 24.6kDa |
AP Mol Mass: | 25 kDa |
Tag: | C-6His |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin Level: | Please contact us for more information. |
Bio Activity: | Testing in progress |
Sequence: | Met142-Gly355 |
Accession: | P12493 |
Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
Formulation: | Supplied as a 0.2 μM filtered solution of PBS, pH7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution: | Not Applicable |
Background: | The HIV1 p24 protein performs highly complex orchestrated tasks during the assembly,budding maturation and infection stages of the viral replication cycle. During viral assembly,the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag p24, the major capsid protein of the HIV-1 virion, has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different isolates. Recombinant HIV1-p24 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. |