Viral Recombinant Proteins

HIV-2 Protease Recombinant Protein (RPPB5603)

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SKU:
RPPB5603
Product Type:
Recombinant Protein
Species:
Viral

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:HIV-2 Protease Recombinant Protein
Product Code:RPPB5603
Size:10µg
Species:HIV-2
Target:Protease
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless clear solution.
Formulation:The HIV-2 Protease solution (0.25mg/1ml) is formulated in 20mM Tris pH7.0, 20mM MES, 200mM NaCl, 1mM EDT, 0.5mM DTT, 0.05% PEG 8000and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.

HIV-2 protease is very significant in the life cycle of the HIV virus. It is expressed in the infected cells as a part of Gag-Pol polyprotein from which it is auto-catalytycaly released after formation of an immature viral particle. The enzyme subsequently cleaves the other parts of viral polyproteins resulting in the maturation of the virus. In HIV-infected patients the enzyme is subjected to intensive mutagenesis and mutants resistant to applied medicines are produced as a result of the selection pressure.

HIV-2 protease is an active homodimer having a molecular mass of 10.7kDa.

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