Histone H4 Polyclonal Antibody
_WB_01__98485__81064.1706547074.jpg?c=1 "Histone H4 Polyclonal Antibody")
- SKU:
- CAB21676
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
_WB_01__98485__81064.1706547074.jpg?c=1&imbypass=on "Histone H4 Polyclonal Antibody")
Description
| Product Name: | Histone H4 Polyclonal Antibody |
| Product Code: | CAB21676 |
| Reactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | 293T |
| Cellular Location: | extracellular exosome, extracellular region, nucleoplasm, nucleus |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Histone H4 (NP_003529.1). |
| Sequence: | MSGRG KGGKG LGKGG AKRHR KVLRD NIQGI TKPAI RRLAR RGGVK RISGL IYEET RGVLK VFLEN VIRDA VTYTE HAKRK TVTAM DVVYA LKRQG RTLYG |
| Synonyms: | H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FA, H4-16, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, HIST1H4A |
| Calculated MW: | 11kDa |
| Observed MW: | 11kDa |
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