Histone H4 Monoclonal Antibody
- SKU:
- CAB23000
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Histone H4 Monoclonal Antibody |
| Product Code: | CAB23000 |
| Reactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57963 |
| Reactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ChIP, ChIP-seq, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:500-1:1000, IF/ICC 1:100-1:500, CHIP 1:50-1:200, ChIP-seq 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, C2C12 |
| Cellular Location: | Chromosome, Nucleus |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Histone H4(NP_003529.1) |
| Sequence: | MSGRG KGGKG LGKGG AKRHR KVLRD NIQGI TKPAI RRLAR RGGVK RISGL IYEET RGVLK VFLEN VIRDA VTYTE HAKRK TVTAM DVVYA LKRQG RTLYG |
| Synonyms: | H4, H4/n, H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4F2, H4FN, FO108, H4-16, H4C11, H4C12, H4C13, H4C15, H4C16, HIST2H4, HIST2H4A |
| Calculated MW: | 11kDa |
| Observed MW: | 11kDa |
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