Histone H2B Antibody (PACO02981)
- SKU:
- PACO02981
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Histone H2B Antibody |
| Antibody SKU: | PACO02981 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from human Histone H2B around the non-acetylation site of K15. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s |
| UniProt Protein Function: | H2BFS: a core component of the nucleoosome. The nucleosome, a basic organizational unit of chromosomal DNA, is octrameric, consisting of two molecules each of histones H2B, H2A, H3, H4. The octamer wraps approximately 147 bp of DNA. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 21q22.3Cellular Component: cytoplasm; extracellular space; nucleoplasm; nucleusMolecular Function: DNA binding; protein heterodimerization activityBiological Process: antibacterial humoral response; defense response to Gram-positive bacterium; innate immune response in mucosa; nucleosome assembly; substantia nigra development |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P57053 |
| NCBI GenInfo Identifier: | 9973351 |
| NCBI Gene ID: | 102724334 |
| NCBI Accession: | P57053.2 |
| UniProt Secondary Accession: | P57053,Q5R2W0, A0AVF9 |
| UniProt Related Accession: | P57053 |
| Molecular Weight: | 13,944 Da |
| NCBI Full Name: | Histone H2B type F-S |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | LOC102724334 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | histone H2B type F-S-like |
| UniProt Protein Name: | Histone H2B type F-S |
| UniProt Synonym Protein Names: | Histone H2B.s; H2B/s |
| Protein Family: | Histone |
| UniProt Gene Name: | H2BFS |
| UniProt Entry Name: | H2BFS_HUMAN |
